What cancer is ifosfamide used for?
Ifosfamide is a cytotoxic, antineoplastic drug used to manage and treat various cancers such as lymphoma, sarcoma, and lung cancer.
What chemo do you give mesna with?
Mesna is always given with ifosfamide. Most people who have treatment with cyclophosphamide are not given doses high enough to cause bleeding from the bladder. They will not need to take mesna. But mesna is given if your treatment involves having high doses of cyclophosphamide.
Why is ifosfamide given?
Ifosfamide is given by an intravenous (IV) infusion (a slow drip through a needle into your port or through a vein in your arm or hand). We use it most commonly in our office for the treatment of uterine cancer and occasionally for cervical cancer or ovarian cancer.
What type of drug is ifosfamide?
Ifosfamide is a chemotherapy drug used to treat many different types of cancer.
What is the brand name for ifosfamide?
Drug Name : Ifosfamide Ifosfamide(Holoxan Inj) generic is an antineoplastic agent, prescribed for certain types of cancer (breast cancer, lymph cancer, lung cancer) in combination with other medicines. It stops the growth of certain cancers.
Why is mesna given ifosfamide?
USES: This medication is used to reduce the risk of bleeding in the bladder (hemorrhagic cystitis), which is a very serious side effect of treatment with a cancer chemotherapy drug called ifosfamide. Mesna helps to protect the lining of the bladder against damage from ifosfamide.
What are the side effects of ifosfamide?
Common side effects
- Increased risk of getting an infection.
- Breathlessness and looking pale.
- Bruising, bleeding gums or nosebleeds.
- Tiredness and weakness (fatigue) during and after treatment.
- Feeling or being sick.
- Loss of appetite.
- Hair loss.
- Irritation of the bladder and kidneys.
Which side effects of ifosfamide limit its use as anticancer agent?
Although ifosfamide has several significant toxic effects, the dose-limiting toxicity is hemorrhagic cystitis. The high incidence of this toxicity requires uroprotection with aggressive hydration, frequent bladder emptying, and the concurrent use of mesna, a uroprotective agent.
How long can you take ifosfamide?
Proper Use This medicine is usually given for 5 consecutive days. This 5-day treatment is given again every 3 weeks or when your body can tolerate it.
What class is ifosfamide?
Ifosfamide is in a class of medications called alkylating agents. It works by slowing or stopping the growth of cancer cells in your body.
How much does ifosfamide cost?
Ifosfamide is a member of the alkylating agents drug class and is commonly used for Cancer, Cervical Cancer, and Testicular Cancer. Brand names for ifosfamide include Ifex….Intravenous Powder For Injection.
| Quantity | Per unit | Price |
|---|---|---|
| 1 | $119.19 | $119.19 |
How fast can you give mesna?
For intermittent oxazaphosphorine therapy following an initial intravenous injection of mesna at a dose of 20% (w/w) of the oxazaphosphorine dose, oral mesna (40% w/w) should be administered at 2 hours and again at 6 hours after the initial intravenous dose.
Is ifosfamide a high-dose chemotherapy?
High-dose ifosfamide as second- or third-line chemotherapy in refractory bone and soft tissue sarcoma patients HDI at a total dose of 14 g/m(2) with mesna is still an active salvage regimen, particularly in patients with synovial sarcomas.
Is ifosfamide a cell cycle drug?
Ifosfamide is chemically related to the nitrogen mustards and is similar in chemical structure to cyclophosphamide. Ifosfamide is an alkylating agent. Alkylating agents are most active in the resting phase of the cell. These drugs are cell-cycle non-specific.
How much ifosfamide will I receive?
Ifosfamide is give through an infusion into a vein (intravenous, IV). The amount of ifosfamide that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition being treated.
What is the difference between ifosfamide and IFEX?
Ifex is the trade name for Ifosfamide. In some cases, health care professionals may use the trade name ifex when referring to the generic drug name ifosfamide. Drug type: Ifosfamide is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug. This medication is classified as an “alkylating agent.”